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DeCS
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Descriptor English:
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Receptors, N-Methyl-D-Aspartate
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Descriptor Spanish:
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Receptores de N-Metil-D-Aspartato
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Descriptor Portuguese:
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Receptores de N-Metil-D-Aspartato
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Synonyms English:
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N Methyl D Aspartate Receptors
N Methylaspartate Receptors
N-Methyl-D-Aspartate Receptors
N-Methylaspartate Receptors
NMDA Receptor Ionophore Complex
NMDA Receptor-Ionophore Complex
NMDA Receptors
Receptors, N Methyl D Aspartate
Receptors, N Methylaspartate
Receptors, N-Methylaspartate
Receptors, NMDA
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Tree Number:
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D12.776.157.530.400.400.500.500
D12.776.543.550.450.500.200.500
D12.776.543.585.400.500.200.500
D12.776.543.750.720.200.450.400.500
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Definition English:
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A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner. The positive voltage dependence of channel conductance and the high permeability of the conducting channel to calcium ions (as well as to monovalent cations) are important in excitotoxicity and neuronal plasticity. |
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History Note English:
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93; was RECEPTOR, N-METHYL-D-ASPARTATE 1991-92; N-METHYL-D-ASPARTATE RECEPTORS was N-METHYL-D-ASPARTATE RECEPTOR see RECEPTOR, N-METHYL-D-ASPARTATE 1991-92
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Allowable Qualifiers English:
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Record Number:
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30889
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Unique Identifier:
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D016194
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Occurrence in VHL:
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Similar:
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DeCS
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